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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
40
Human Site:
Y946
Identified Species:
58.67
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
Y946
S
V
M
D
G
K
E
Y
Q
A
G
R
F
A
R
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
Y997
S
V
M
D
G
K
E
Y
Q
A
G
R
F
A
R
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
Y946
S
V
M
G
G
E
K
Y
Q
A
G
R
F
A
Q
Dog
Lupus familis
XP_545291
1075
123911
Y947
S
V
M
D
G
Q
A
Y
P
A
G
R
F
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
Y946
S
V
M
D
G
K
E
Y
Q
A
G
R
F
A
R
Rat
Rattus norvegicus
P70496
1074
123795
Y946
S
V
M
D
G
K
E
Y
Q
A
G
R
F
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
F210
S
Q
Q
G
L
A
E
F
D
E
D
K
G
S
V
Chicken
Gallus gallus
XP_422793
1072
123414
Y945
S
V
M
D
G
E
A
Y
S
A
G
R
F
A
Q
Frog
Xenopus laevis
NP_001129642
1039
119219
Y911
S
V
M
D
G
E
T
Y
E
A
G
K
F
A
L
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
Y894
S
V
M
D
G
Q
E
Y
Q
A
G
K
F
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
Y1231
G
R
M
N
G
K
K
Y
P
S
G
V
F
A
G
Honey Bee
Apis mellifera
XP_001121004
1135
129725
F1006
G
R
M
N
D
I
P
F
P
C
G
K
F
A
G
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
F1291
S
V
M
D
G
K
P
F
E
A
G
R
F
A
K
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
R705
F
Y
N
D
T
W
I
R
I
A
V
T
N
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
W902
S
S
M
N
G
M
K
W
M
A
G
K
F
S
Y
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
Y1146
T
K
M
N
G
D
D
Y
Y
A
G
K
F
P
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
100
73.3
80
N.A.
100
93.3
N.A.
13.3
73.3
66.6
80
N.A.
46.6
26.6
73.3
13.3
P-Site Similarity:
100
100
93.3
86.6
N.A.
100
100
N.A.
33.3
86.6
86.6
93.3
N.A.
66.6
46.6
93.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
13
0
0
82
0
0
0
75
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
63
7
7
7
0
7
0
7
0
0
0
0
% D
% Glu:
0
0
0
0
0
19
38
0
13
7
0
0
0
0
0
% E
% Phe:
7
0
0
0
0
0
0
19
0
0
0
0
88
0
0
% F
% Gly:
13
0
0
13
82
0
0
0
0
0
88
0
7
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
7
0
7
0
0
0
0
0
0
% I
% Lys:
0
7
0
0
0
38
19
0
0
0
0
38
0
0
7
% K
% Leu:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
13
% L
% Met:
0
0
88
0
0
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
7
25
0
0
0
0
0
0
0
0
7
0
7
% N
% Pro:
0
0
0
0
0
0
13
0
19
0
0
0
0
7
0
% P
% Gln:
0
7
7
0
0
13
0
0
38
0
0
0
0
0
19
% Q
% Arg:
0
13
0
0
0
0
0
7
0
0
0
50
0
0
25
% R
% Ser:
75
7
0
0
0
0
0
0
7
7
0
0
0
13
0
% S
% Thr:
7
0
0
0
7
0
7
0
0
0
0
7
0
7
0
% T
% Val:
0
63
0
0
0
0
0
0
0
0
7
7
0
0
7
% V
% Trp:
0
0
0
0
0
7
0
7
0
0
0
0
0
0
7
% W
% Tyr:
0
7
0
0
0
0
0
69
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _